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  Progress in Chemistry, 2010, Vol. 22, Issue (11) : 2165-2172 Current Issue | Next Issue | Archive  
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  . Molecularly Imprinted Functional Materials Based on Polysaccharides  Progress in Chemistry, 2010, 22(11): 2165-2172
  王红飞 张黎明. 多糖基分子印迹功能材料*  化学进展, 2010, 22(11): 2165-2172
Review
Molecularly Imprinted Functional Materials Based on Polysaccharides
Wang Hongfei  Zhang Liming**
(School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China)
Abstract:

In recent years, molecularly imprinted materials (MIMs) based on polysaccharides have attracted great attention due to their abundant raw materials, good biodegradability and biocompatibility. In this paper, the preparation methods of MIMs based on natural polysaccharides such as cyclodextrin, chitosan, cellulose, alginic acid, agarose and starch are reviewed, including direct crosslinking, graft-copolymerization crosslinking and sol-gel technique. Their applications in separation, solid phase extraction, biosensing, drug delivery and protein refolding are discussed. In addition, the development trend of polysaccharide-based MIMs is prospected.

Contents
1 Introduction
2 Preparation methods of MIMs
2.1 Direct crosslinking
2.2 Graft-copolymerization crosslinking
2.3 Sol-gel technique
3 Applications of MIMs
3.1 Metal ion separation
3.2 Chiral separation
3.3 Peptide and protein separation
3.4 Solid phase extraction
3.5 Biosensing
3.6 Drug delivery
3.7 Protein refolding
4 Prospect

Key words: polysaccharides   molecular imprinting   functional materials  
Received: 2010-02-24  Revised: 2010-04-30  Published: 2010-10-20
Corresponding Authors: Zhang Liming     Email: cedc61@zsu.edu.cn; ceszhlm@mail.sysu.edu.cn
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