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  Progress in Chemistry, 2011, Vol. 23, Issue (8) : 1769-1781 Current Issue | Next Issue | Archive  
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  Jiang Guoxiang, Shen Zhenyao, Niu Junfeng, Zhuang Lingping, He Tiande. Nanotoxicity of Engineered Nanomaterials in the Environment  Progress in Chemistry, 2011, 23(8): 1769-1781
  蒋国翔, 沈珍瑶, 牛军峰, 庄玲萍, 何天德. 环境中典型人工纳米颗粒物毒性效应  化学进展, 2011, 23(8): 1769-1781
Nanotoxicity of Engineered Nanomaterials in the Environment
Jiang Guoxiang, Shen Zhenyao, Niu Junfeng*, Zhuang Lingping, He Tiande
State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, China

As the technological benefits of nanotechnology begin to rapidly move from laboratory to large-scale industrial application, release of nanomaterials to the environment including water, soil, sediment, and biosolids is inevitable. Concerns have been raised that the special properties of nanostructured materials that make them so attractive could potentially lead to unforeseen health risk or environmental hazards. The progress on the sources of nanoparticles, physicochemical properties and environmental or health risk is critically reviewed in this work. The environmental behavior of nanoparticles is analyzed when they are released into the aqueous environment. Toxicological effects of typical nanoparticles on bacteria, aquatic organisms, soil animals and mammalian cells are summarized. The possible toxicological mechanisms on these model microbes are then discussed. Furthermore, the relationships between toxicological effects of nanoparticles on model microbe and self-physicochemical/environmental factors are critically analyzed. The challenges and existing problems of nanotoxicity research are listed. Moreover, we also highlight the future research fields (such as quantitative structure activity relationship, QSAR) need regarding nanoparticles in the environment. It has been point out that more studies are urgently needed to scrutinize the characteristic methods of nanoscale materials and long-term research on the behavior and toxicity of nanoparticles in microbial community.

1 Introduction
2 Properties, sources and toxicity of nanomaterials
2.1 Properties
2.2 Sources
2.3 Environmental behaviors
2.4 Toxicological effects
3 Toxicity mechanisms of nanomaterials
3.1 Effects of size-dependent
3.2 Effects of generated ROS oxidation damage and oxidative stress
3.3 Effects of dissolved metal ions
4 Influence factors
4.1 Characteristics
4.2 Environmental factors
5 Existing problems and prospect

Key words: engineered nanomaterials   nanotoxicity   natural organic matter (NOM)   aggregation   dispersion  
Received: 2010-10-01  Revised: 2010-12-01 
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