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  Progress in Chemistry, 2008, Vol. 20, Issue (05) : 747-753 Current Issue | Next Issue | Archive  
  Cite this paper:
  Li Zhenying|Duan Hongquan|Huang Yanping|Liu Zhaosheng**. Monolithic Column for High Performance Liquid Chromatography  Progress in Chemistry, 2008, 20(05): 747-753{, DOI: }
  李振莹,段宏泉,黄艳萍,刘照胜. 分子印迹液相色谱整体柱*  化学进展, 2008, 20(05): 747-753{, DOI: }
Review
Monolithic Column for High Performance Liquid Chromatography
Li Zhenying; Duan Hongquan; Huang Yanping; Liu Zhaosheng**
(College of Pharmacy, Tianjin Medical University, Tianjin 300070, China)
Abstract: Molecular imprinting is a new approach to prepare predictable selectivity stationary and monolithic collumn is a novel technology for chromatographic stationary phase. The combination of monolith and molecularly imprinted polymers(MIPs) integrates the high efficiency of liquid chromatography and the high selectivity of MIPs, which will accelerates the develpoment of MIPs technique in the field of separation science. Therefore, the research in this field has attracted considerable interests and plays an important role in the area of analytical chemistry. In this review,the progress of molecularly imprinted monolith is summarized in detail from the polymerization conditionsto prepare MIPs' physical monolith, the separation conditions to evaluate the efficiency of MIPs, and the method of characterizingg MIPs' physical and chemical properties concerning the application of liquid chromatography-based MIPs. The limitations and prospective applications of the technique relates with MIPs monolithic column are also discussed.
Key words: molecularly imprinted polymers   monolithic columns   liquid chromatography   in-situ polymerization  
Received: 2007-06-01  Revised: 2007-07-25 
Corresponding Authors: Liu Zhaosheng
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Articles by Li Zhenying; Duan Hongquan; Huang Yanping; Liu Zhaosheng
Articles by Li Zhenying; Duan Hongquan; Huang Yanping; Liu Zhaosheng
Articles by Li Zhenying; Duan Hongquan; Huang Yanping; Liu Zhaosheng
Articles by Li Zhenying; Duan Hongquan; Huang Yanping; Liu Zhaosheng
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